Introduction of Jianke Li

编辑:admin   日期:2017/12/11 15:27:33   浏览次数:?(次)   【       默认

Prof. Dr. Jianke Li is now the Chief Scientist of innovation team of honeybee proteomics of Agricultural Science and Technology Innovation Program in China. He is also scientist of the key state project of the earmarked fund for Modern Agro-Industry Technology Research System in China. The major research interests are revealing the molecular basis of honeybee biology. The team he led is now becoming the leader in the honeybee proteomics around the globe. More than 40 papers of honeybee proteomic research have published in high rank international journal such as Molecular Cellular Proteomics and Journal of proteome research, and the total impact factor is over 190. He is now a reviewer of Journal of Proteome Research, Journal of Proteomics ect. “Revealing the mechanism of the high yield and biochemical characteristics of royal jelly” is awarded the second price of scientific and technological achievements by Beijing committee of science and technology in 2013. Of the graduate students he guided, including 8 international students, several of them are awarded as excellent ones by CAAS.


Institute of Apicultural Research, Chinese Academy of Agricultural Science No.8 Admin. building, 12 Zhonghuancun South Avenue, Beijing 100081, China

Email: apislijk@126.com

Research Interests

Applying proteomics, genomics and gene editing tools to decipher molecular mechanism of honeybee biology and function of royal jelly for honeybee and human health promotion.


2000.09-2003.07  Ph.D Honeybee science     Zhejiang University

1993.09-1996.07  M. Sc Animal environment   China Agricultural University

Work Experience

2005--   : Chief scientist  Institute of Apicultural Research, CAAS.

2000-2005: Professor  Zhengzhou University, Henan, China.

1983-2005: Teacher  Zhengzhou College of Animal Husbandry


2005: Talented young scientist approved by year

Publication: (First and correspondence author listed)

1.      Meng L, Huo X, Feng M, Fang Y, Han B, Hu H, Wu F, Li J. Proteomics Reveals the Molecular Underpinnings of Stronger Learning and Memory in Eastern Compared to Western Bees. Mol Cell Proteomics. 2017 Nov 29. pii: mcp.RA117.000159. doi: 10.1074/mcp.RA117.000159 (IF 6.52)

2.      Ararso Z, Ma C, Qi Y, Feng M, Han B, Hu H, Meng L, Li J. Proteome Comparisons between Hemolymph of Two Honeybee Strains (Apis mellifera ligustica) Reveal Divergent Molecular Basis in Driving Hemolymph Function and High Royal Jelly Secretion. J Proteome Res. 2017 Dec 5. doi: 10.1021/acs.jproteome.7b00621. (IF 4.3)

3.      Han B, Fang Y, Feng M, Hu H, Hao Y, Ma C, Huo X, Meng L, Zhang X, Wu F, Li J. Brain Membrane Proteome and Phosphoproteome Reveal Molecular Basis Associating with Nursing and Foraging Behaviors of Honeybee Workers. J Proteome Res. 2017 16, 3646−63 (IF 4.3)

4.      Bezabih G, Cheng H, Han B, Feng M, Xue Y, Hu HanLi J. Phosphoproteome Analysis Reveals Phosphorylation Underpinnings in the Brains of Nurse and Forager Honeybees (Apis mellifera). Sci Rep 2017, 16:1973. (IF 4.3)

5.      Fan P, Han B, Feng M, Fang Y, Zhang L, Hu H, Hao Y, Qi Y, Zhang X, Li J. Functional and Proteomic Investigations Reveal Major Royal Jelly Protein 1 Associated with Anti-hypertension Activity in Mouse Vascular Smooth Muscle Cells. Sci Rep. 2016, 6: 30230. (IF 5.2)

6.      Hu H, Bienefeld K, Wegener J, Zautke F, Hao Y, Feng M, Han B, Fang Y, Wubie AJ, Li J. Proteome analysis of the hemolymph, mushroom body, and antenna provides novel insight into honeybee resistance against Varroa infestation. J Proteome Res. 2016, 15(8): 2841-54. (IF 4.2)

7.      Huo X, Wu B, Feng M, Han B, Fang Y, Hao Y, Meng L, Wubie AJ, Fan P, Hu H, Qi Y, Li J. Proteomic Analysis Reveals the Molecular Underpinnings of Mandibular Gland Development and Lipid Metabolism in Two Lines of Honeybees (Apis mellifera ligustica). J Proteome Res. 2016, 15(9):3342-57. (IF 4.2)

8.      Feng M, Fang Y, Han B, Xu X, Fan P, Hao Y, Qi Y, Hu H, Huo X, Meng L, Wu B, Li J. In-Depth N-Glycosylation Reveals Species-Specific Modifications and Functions of the Royal Jelly Protein from Western (Apis mellifera) and Eastern Honeybees (Apis cerana). J Proteome Res. 2015, 14(12):5327-40. (IF 4.23)

9.      Qi Y, Fan P, Hao Y, Han B, Fang Y, Feng M, Cui Z, Li J. Phosphoproteomic Analysis of Protein Phosphorylation Networks in the Hypopharyngeal Gland of Honeybee Workers (Apis mellifera ligustica). J Proteome Res. 2015, 14(11): 4647-61. (IF 4.23)

10.  Han B, Fang Y, Feng M, Hu H, Qi Y, Huo X, Meng L, Wu B, Li J. Quantitative Neuropeptidome Analysis Reveals Neuropeptides Are Correlated with Social Behavior Regulation of the Honeybee Workers. J Proteome Res. 2015, 14(10): 4382-93. (IF 4.23)

11.  Fang Y, Feng M, Han B, Qi Y, Hu H, Fan P, Huo X, Meng L, Li J. Proteome Analysis Unravels Mechanism Underling the Embryogenesis of the Honeybee Drone and Its Divergence with the Worker (Apis mellifera lingustica). J Proteome Res. 2015, 14(9):4059-71. (IF 4.23)

12.  Han B, Fang Y, Feng M, Lu X, Huo X, Meng L, Wu B, Li J. In-depth Phosphoproteomic Analysis of Royal Jelly Derived from Western and Eastern Honeybee Species. J Proteome Res. 2014, 13 (12), 5928–5943 (IF 5.1).

13.  Fang Y, Feng M, Han B, Lu X, Ramadan H, Li J. In-depth Proteomics Characterization of Embryogenesis of the Honey Bee Worker (Apis mellifera L.). Mol Cell Proteomics. 2014, 13 (9): 2306-2320. (IF 7.25)

14.  Feng M, Ramadan H, Han B, Fang Y, Li J. Hemolymph proteome changes during worker brood development match the biological divergences between western honey bees (Apis mellifera) and eastern honey bees (Apis cerana). BMC Genomics, 2014, 2014, 15:563 (IF 4.4).

15.  Zhang L, Han B, Li R, Lu X, Fang Y, Feng M, Li J. Comprehensive identification of novel proteins and N-glycosylation sites in royal jelly. BMC Genomics, 2014, 15:135. (IF 4.4)

16.  Zheng A, Luo J, Meng K, Li J, Zhang S, Li K, Liu G, Cai H, Bryden W, Yao B. Proteome changes underpin improved meat quality and yield of chickens (Gallus gallus) fed the probiotic Enterococcus faecium. BMC Genomics, 2014, 15:1167. (IF 4.4)

17.  Li R, Zhang L, Fang Y, Han B, Lu X, Zhou T, Feng M, Li J. Proteome and phosphoproteome analysis of honeybee (Apis mellifera) venom collected from electrical stimulation and manual extraction of the venom gland. BMC genomics, 2013, 14(1), 766. (IF 4.4)

18.  Gala A, Fang Y, Woltedji D, Zhang L, Han B, Feng M, Li J. Changes of Proteome and Phosphoproteome Trigger Embryo-larva Transition of Honeybee Worker (Apis mellifera ligustica). J Proteomics. 2013, 78, 428-46. (IF 4.9)

19.  Han B, Zhang L, Feng M, Fang Y, Li J. An Integrated Proteomics Reveals Pathological Mechanism of Honeybee (Apis cerena) Sacbrood Disease. J Proteome Res. 2013, 12, 1881-97. (IF 5.1)

20.  Woltedji D, Fang Y, Han B, Feng M, Li R, Gala A, Li J. Proteome Analysis of Hemolymph Changes during the Larval to Pupal Development Stages of Honeybee Workers (Apis mellifera ligustica). J Proteome Res. 2013, 12(11), 5189-98. (IF 5.1)

21.  Feng M, Fang Y, Han B, Zhang L, Lu X, Li J. Novel aspects of understanding molecular working mechanisms of salivary glands of worker honeybees (Apis mellifera) investigated by proteomics and phosphoproteomics. J Proteomics. 2013; 87, 1-15. (IF 4.1)

22.  Li H, Zhang L, Ni C, Shang H, Zhuang S, Li J.Molecular recognition of floral volatile with two olfactory related proteins in the Eastern honeybee (Apiscerana). Int J Biol Macromol, 2013, 56: 114-21.(IF 2.6)

23.  Begna D, Han B, Feng M, Fang Y, Li J. Differential Expressions of Nuclear Proteomes between Honeybee (Apis mellifera L.) Queen and Worker Larvae: A Deep Insight into Caste Pathway Decisions. J. Proteome Res. 2012, 11 (2), 1317-29. (IF 5.1)

24.  Woltedji D, Song F, Zhang L, Gala A, Han B, Feng M, Fang Y, Li J. Western Honeybee Drones and Workers (Apis mellifera ligustica) Have Different Olfactory Mechanisms than Eastern Honeybees (Apis cerana cerana). J Proteome Res. 2012, 11, 4526-40. (IF 5.1)

25.  Zhang L, Fang Y, Li R, Feng M, Han B, Zhou T, Li J. Towards posttranslational modification proteome of royal jelly. J Proteomics. 2012, 75, 5327-41. (IF 4.9)

26.  Fang Y, Song F, Zhang L, Woltedji D, Han B, Feng M, Li J. Differential antennal proteome comparison of adult honeybee drone, worker and queen (Apis mellifera L.). J. Proteomics, 2012, 75, 756-73. (IF 4.9)

27.  Begna D, Fang Y, Feng M, Li J. Mitochondrial Proteins Differential Expression during Honeybee (Apis mellifera L.) Queen and Worker Larvae Caste Determination. J. Proteome Res. 2011, 10(9):4263-80. (IF 5.46)

28.  Feng M, Song F, Aleku D, Han B, Fang Y, Li J. Antennal Proteome Comparison of Sexually Mature Drone and Forager Honeybees. J. Proteome Res. 2011, 10(7):3246-60. (IF 5.46)

29.  Zheng A, Li J, Begna D, Fang Y, Feng M, Song F. Proteomic Analysis of Honeybee (Apis mellifera L.) Pupae Head Development. PLoS ONE, 2011, 6(5): e20428. (IF 4.4)

30.  Li J, Fang Y, Zhang L, Begna D. Honeybee (Apis mellifera ligustica) drone embryo proteomes. J. Insect Physiol, 2011, 57 (3), 372-84. (IF 2.31)

31.  Han B, Li C, Zhang L, Fang Y, Feng M, Li J. Novel Royal Jelly Proteins Identified by Gel-Based and Gel-free Proteomics. J. Agric. Food Chem. 2011; 59(18):10346-55. (IF 2.816)

32.  Fang Y, Feng M, Li J. Royal jelly proteome comparison between A. mellifera ligustica and A. cerana cerana. J.Proteome Res. 2010, 9(5):2207-15. (IF 5.132)

33.  Li J, Feng M, Begna D, Fang Y. Proteome comparison of hypopharyngeal gland development between Italian and royal jelly producing worker honeybees (Apis mellifera L.). J. Proteome Res. 2010, 9(12), 6578-94. (IF 5.132)

34.  Li J, Wu J, Begna D, Song F, Zheng A, Fang Y. Differential Protein Expression in Honeybee (Apis mellifera L.) Larvae: Underlying Caste Differentiation. PLoS ONE, 2010, 5(10): e13455. (IF 4.35)

35.  Feng M, Fang Y, Li J. Proteomic analysis of honeybee worker (Apis mellifera) hypopharyngeal gland development. BMC Genomics. 2009, 10: 645. (IF 4.07)

36.  Li J, Zhang L, Feng M, Zhang Z, Pan Y. Identification of the proteome composition occurring during the course of embryonic development of bees (Apis mellifera). Insect Mol Biol., 2009, 18 (1): 1-9. (IF 2.787)

37.  Li J, Feng M, Zhang L, Pan Y. Proteomics analysis of major royal jelly protein changes under different storage conditions. J. Proteome Res. 2008, 7 (8), 3339–3353. (IF 5.675)

38.  Li J, Chen J, Zhang Z, Pan Y. Proteome Analysis of Tea Pollen (Camellia sinensis) under Different Storage Conditions. J. Agric. Food Chem. 2008, 56, 7535-44. (IF 2.532)

39.  Li J. Feng M, Zhang Z, Pan Y. Identification of proteome complement of hypopharyngeal gland from two species of worker bees (Apis mellifera). Apidologie. 2008, 39(2): 199-214. (IF 2.2)

40.  Li J, Wang T. Comparative analysis of the effects of different storage conditions on major royal jelly proteins. J. Apicul. Res. 2007, 46: 73-80. (IF 0.75)

41.  Li J. Li H, Zhang Z, Pan Y. Identification of the proteome complement of the higher royal jelly producing bees (Apis mellifera L.) during the worker larvae development. Apidologie, 2007, 38(6): 545-557. (IF 2.2)

42.  Li J. Wang T, Zhang Z, Pan Y. Proteomic Analysis of Royal Jelly from Three Strains of Western Honeybees (Apis mellifera). J. Agric. Food Chem. 2007, 55, 8411-22. (IF 2.322)

43.  Wu Jie, Li Jilian, Peng Wenjun, Li Jianke. (2006). Major honey plants and their utilization (part 1). American Bee Journal, 146(1): 59-64.


Last update: December 5, 2017

Quick Link
Copyright © Honeybee Proteomics Team · Institute of Apicultural Research, Chinese Academy of Agricultural Sciences, Beijing, China.